CancerTYPE ID is a standardized, objective molecular test based on the differential expression of 92 genes that classifies tumors by matching the gene expression pattern of a patients tumor tissue to a database of known tumor types and histological subtypes. The test analyzes the expression of a panel of 92 genes from a tumor specimen of under ~300 cells through a unique technique called RT-PCR. A high-throughput, real-time RT-PCR method was developed to analyze the expression of select genes.
Formalin-fixed paraffin embedded tissue block from patient is sectioned to prepare an H&E slide and three unstained slides. Pathologist inspects the H&E slide to determine tumor regions for microdissection.
Pathologist delineates tumor areas destined for microdissection. Trained histotechnologists perform dissection (micro/manual) to acquire tumor cells indicated by pathologist.